Influence of simulated tear flow on ocular penetration of transfersomes.
Barbalho; Brugger; Gratieri; Keck; Rupenthal; Agarwal · 2026 · European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Transfersomes are deformable lipid vesicles extensively evaluated for transdermal drug delivery. However, the ocular penetration mechanism of transfersomes is poorly understood as the effect of tear flow, which by altering osmotic…
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Metadata source: PubMed · DOI 10.1016/j.ejpb.2026.115154