Association between the extent of intrapulmonary spread on chest CT and false-negative results of T-SPOT.TB in pulmonary tuberculosis: a retrospective study.
Sato R; Takasaka N; Hosaka Y; Fukuda T; Shinfuku K; Takatsuka M; Hasegawa T; Yamada M · 2025 · BMC infectious diseases
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background The T-SPOT.TB assay is widely used for the adjunctive diagnosis of tuberculosis (TB). However, clinicians often encounter false-negative T-SPOT.TB results. The extent of TB spread may influence host immune functions, which can…
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Metadata source: Europe PMC · DOI 10.1186/s12879-025-10777-x