Population pharmacokinetic/pharmacodynamic modelling to evaluate favipiravir in combination with lopinavir-ritonavir in patients with COVID-19.
Agyeman AA; Buggiotti L; Brown LK; Guerra-Assuncao JA; Kembou-Ringert JE; Mak WY; Breuer J; Lowe DM · 2026 · British journal of clinical pharmacology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Aims The repurposed use of favipiravir in COVID-19 has been reported to have limited clinical efficacy, yet it has been widely used in some countries. Favipiravir causes mutagenesis in RNA viruses, and it is currently unknown whether it…
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Metadata source: Europe PMC · DOI 10.1002/bcp.70507