Bronchoalveolar lavage fluid and serum 1,3-β-d-glucan testing for invasive pulmonary aspergillosis diagnosis in hematological patients: the role of factors affecting assay performance
Barbora Weinbergerová; Tomáš Kabut; Iva Kocmanová; Martina Lengerová; Zdeněk Pospı́šil; Zdeněk Král; Jiřı́ Mayer · 2020 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Invasive fungal disease (IFD) early diagnosis improves hematological patient survival. Non-culture-based methods may reduce diagnostic time to identify IFD. As complex data on the value of 1,3-β-D-glucan (BDG) from bronchoalveolar lavage fluid (BALF) compared to serum for the most frequent invasive pulmonary aspergillosis (IPA) diagnosis are scarce, particularly including evaluation of potential factors adversely affecting BDG assay, we provided prospective single-center analysis evaluating 172 episodes of pulmonary infiltrates with BDG detection in BALF and serum samples collected in parallel
Abstract by Barbora Weinbergerová; Tomáš Kabut; Iva Kocmanová; Martina Lengerová; Zdeněk Pospı́šil; Zdeněk Král; Jiřı́ Mayer, Scientific Reports (2020) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41598-020-75132-3