Safety, Efficacy, and Immunogenicity of a Multivalent Adjuvanted S. aureus Vaccine in Adults with Recent Skin And Soft Tissue Infections: An Observer-blind, Randomized, Placebo-controlled, Multinational Phase 1/2 Trial.
Athan E; Greenberg RN; Baker DA; Shah R; Dubhashi S; Badat A; Thurlow C; Schlessinger J · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background A vaccine that prevents Staphylococcus aureus skin and soft tissue infections (SA-SSTIs) would have a major impact on public health. Methods A two-part randomized study began with a phase 1, first-in-human, dose-escalation that…
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Metadata source: Europe PMC · DOI 10.1093/cid/ciag162