Diffusion and Perfusion MRI to Differentiate Treatment-Related Changes Including Pseudoprogression from Recurrent Tumors in High-Grade Gliomas with Histopathologic Evidence
Alisa J. Prager; Nina Martinez; Kathryn Beal; Antonio Omuro; Z. Zhang; Robert J. Young · 2015 · American Journal of Neuroradiology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND AND PURPOSE: Treatment-related changes and recurrent tumors often have overlapping features on conventional MR imaging. The purpose of this study was to assess the utility of DWI and DSC perfusion imaging alone and in combination to differentiate treatment-related effects and recurrent high-grade gliomas. MATERIALS AND METHODS: We retrospectively identified 68 consecutive patients with high-grade gliomas treated by surgical resection followed by radiation therapy and temozolomide, who then developed increasing enhancing mass lesions indeterminate for treatment-related changes versus
Abstract by Alisa J. Prager; Nina Martinez; Kathryn Beal; Antonio Omuro; Z. Zhang; Robert J. Young, American Journal of Neuroradiology (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3174/ajnr.a4218