Multi-ancestry genome-wide association study of topiramate's effects on heavy alcohol use.
Davis CN; Jinwala Z; Justice AC; Rentsch CT; Kranzler HR · 2025 · Alcohol, clinical & experimental research
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Topiramate reduces alcohol consumption in individuals who drink heavily. Candidate gene studies aimed at identifying genetic variants that predict topiramate's effects on drinking have yielded inconsistent findings. To identify…
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Metadata source: Europe PMC · DOI 10.1111/acer.70069