Identification of biomarkers of response to abatacept in patients with SLE using deconvolution of whole blood transcriptomic data from a phase IIb clinical trial
Somnath Bandyopadhyay; Seán Connolly; Omar Jabado; June Ye; Sheila Kelly; Michael A. Maldonado; René Westhovens; Peter Nash · 2017 · Lupus Science & Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
OBJECTIVE: To characterise patients with active SLE based on pretreatment gene expression-defined peripheral immune cell patterns and identify clusters enriched for potential responders to abatacept treatment. METHODS: This post hoc…
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Metadata source: OpenAlex · DOI 10.1136/lupus-2017-000206