Optimal duration of neoadjuvant chemotherapy prior to CRS ± HIPEC for colorectal cancer: An assessment of survival and postoperative outcomes.
Bennett FJ; Oppat KM; Zaidi MY; Winer J; Russell MC; Staley C; Maithel SK; Concors SJ · 2026 · Surgical oncology insight
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Cytoreductive surgery (CRS) with or without heated intraperitoneal chemotherapy (HIPEC) represents a viable therapy for select patients with colorectal cancer (CRC) peritoneal metastases. Given recurrence rates, challenges…
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Metadata source: Europe PMC · DOI 10.1016/j.soi.2025.100210