Abnormalities of lipid metabolism in the progression and treatment of depression
Xinchi Luan; Xuezhe Wang; Ying Shi; Xinyi Zhang; Yilin Wang; Miao Zhou; Zhaoyi Wu; Zijiao Liu · 2025 · Frontiers in Psychiatry
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Depression represents a global health challenge with complex etiology and significant societal impact. Recent advancements reveal a critical role of lipid metabolism dysregulation in the pathogenesis and severity of depressive disorders. This review elucidates the impact of lipid imbalance on depression highlighting how dyslipidemia not only makes individuals prone to depression but also exacerbates the progression of depression (including the occurrence of some comorbidities of depression). On this basis, we have summarized that abnormal lipid metabolism may serve as a diagnostic and therapeu
Abstract by Xinchi Luan; Xuezhe Wang; Ying Shi; Xinyi Zhang; Yilin Wang; Miao Zhou; Zhaoyi Wu; Zijiao Liu, Frontiers in Psychiatry (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.3389/fpsyt.2025.1589663