e-ISSN: Pending
Negative / Null Result ReportMedicine· cited by 1,061

RIBBON-1: Randomized, Double-Blind, Placebo-Controlled, Phase III Trial of Chemotherapy With or Without Bevacizumab for First-Line Treatment of Human Epidermal Growth Factor Receptor 2–Negative, Locally Recurrent or Metastatic Breast Cancer

Nicholas J. Robert; Véronique Dièras; John A. Glaspy; Adam Brufsky; Igor Bondarenko; Oleg Lipatov; Edith A. Perez; Denise A. Yardley · 2011 · Journal of Clinical Oncology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

PURPOSE: This phase III study compared the efficacy and safety of bevacizumab (BV) when combined with several standard chemotherapy regimens versus those regimens alone for first-line treatment of patients with human epidermal growth…

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Metadata source: OpenAlex · DOI 10.1200/jco.2010.28.0982