A validation study of crescents in predicting ESRD in patients with IgA nephropathy
Xiaoyan Zhang; Sufang Shi; Yan Ouyang; Meng Yang; Manman Shi; Xiaoxia Pan; Jicheng Lv; Zhaohui Wang · 2018 · Journal of Translational Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: A working group on the Oxford classification of IgA nephropathy (IgAN) recently reported that crescents detected in kidney tissue predicted a worse renal outcome. However, this finding must be validated in independent cohorts before it can be widely applied to clinical practice. METHODS: Biopsy-proven IgAN patients were continuously recruited from two large renal centers in China from 1989 to 2014. All patients were followed for more than 1 year unless end stage renal disease (ESRD) occurred within 12 months. Crescents were defined as focal cellular or fibrocellular crescent format
Abstract by Xiaoyan Zhang; Sufang Shi; Yan Ouyang; Meng Yang; Manman Shi; Xiaoxia Pan; Jicheng Lv; Zhaohui Wang, Journal of Translational Medicine (2018) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/s12967-018-1488-5