A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity
Fiona Smaill; Mangalakumari Jeyanathan; Marek Smieja; Maria Fe C. Medina; Niroshan Thanthrige-Don; Anna Zganiacz; Cindy Yin; Armando Heriazon · 2013 · Science Translational Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
There is an urgent need to develop new tuberculosis (TB) vaccines to safely and effectively boost Bacille Calmette-Guérin (BCG)-triggered T cell immunity in humans. AdHu5Ag85A is a recombinant human type 5 adenovirus (AdHu5)-based TB…
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Metadata source: OpenAlex · DOI 10.1126/scitranslmed.3006843