The effects of a novel nutraceutical combination on low-density lipoprotein cholesterol and other markers of cardiometabolic health in adults with hypercholesterolaemia: A randomised double-blind placebo-controlled trial
Welma Stonehouse; Bianca Benassi-Evans; Jennie Louise · 2025 · Atherosclerosis
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
BACKGROUND AND AIM: Clinical evidence exists for LDL-cholesterol lowering by plant sterols, bergamot extract and artichoke leaf extract individually but their effect when combined is unknown. This study investigated the effects of a novel…
Excerpt shown for reference under fair use — read the full paper at the publisher.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Solvent‐Free Ball‐Milling Biginelli Reaction by Subcomponent Synthesis
Negative / Null Result ReportNovel psychoactive substance consumption is more represented in bipolar disorder than in psychotic disorders: A multicenter‐observational study
Negative / Null Result ReportAcute liver failure
Negative / Null Result ReportA Lack of Significant Effect of POR*28 Allelic Variant on Tacrolimus Exposure in Kidney Transplant Recipients
Negative / Null Result ReportMenthol concentration in topical cold gel does not have significant effect on skin cooling
Negative / Null Result ReportDevelopment of a digital twin of a tablet that mimics a real solid dosage form: Differences in the dissolution profile in conventional mini-USP II and a biorelevant colon model
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1016/j.atherosclerosis.2025.119177
