Melatonin and Metformin Failed to Modify the Effect of Dacarbazine in Melanoma.
Novik AV; Protsenko SA; Baldueva IA; Berstein LM; Anisimov VN; Zhuk IN; Semenova AI; Latipova DK · 2021 · The oncologist
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
The finding, in one line
“Lessons learned Melatonin did not increase the efficacy of systemic chemotherapy in melanoma.”
Abstract (excerpt)
Lessons learned Melatonin did not increase the efficacy of systemic chemotherapy in melanoma. Metformin did not increase the efficacy of systemic chemotherapy in melanoma. Background Current data support the possibility of antitumor…
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WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: Europe PMC · DOI 10.1002/onco.13761