High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer β-amyloid peptide
Sabine Rauth; Dominik Hinz; Michael A. Borger; Markus Uhrig; Manuel Mayhaus; Matthias Riemenschneider; Arne Skerra · 2016 · Biochemical Journal
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Amyloid beta (Aβ) peptides, in particular Aβ42 and Aβ40, exert neurotoxic effects and their overproduction leads to amyloid deposits in the brain, thus constituting an important biomolecular target for treatments of Alzheimer's disease…
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Metadata source: OpenAlex · DOI 10.1042/bcj20160114