Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior
Jessica E. Salvatore; Alexis C. Edwards; Jeanette N. McClintick; Tim B. Bigdeli; Amy Adkins; Fazil Alıev; Howard J. Edenberg; Tatiana Foroud · 2015 · Translational Psychiatry
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Adult antisocial behavior (AAB) is moderately heritable, relatively common and has adverse consequences for individuals and society. We examined the molecular genetic basis of AAB in 1379 participants from a case-control study in which the cases met criteria for alcohol dependence. We also examined whether genes of interest were expressed in human brain. AAB was measured using a count of the number of Antisocial Personality Disorder criteria endorsed under criterion A from the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV). Participants were genotyped on the Illumi
Abstract by Jessica E. Salvatore; Alexis C. Edwards; Jeanette N. McClintick; Tim B. Bigdeli; Amy Adkins; Fazil Alıev; Howard J. Edenberg; Tatiana Foroud, Translational Psychiatry (2015) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Reproducible brain-wide association studies require thousands of individuals
Negative / Null Result ReportDaily Left Prefrontal Transcranial Magnetic Stimulation Therapy for Major Depressive Disorder
Negative / Null Result ReportEarly Brain Overgrowth in Autism Associated With an Increase in Cortical Surface Area Before Age 2 Years
Negative / Null Result ReportObjective evaluation of anosmia and ageusia in COVID‐19 patients: Single‐center experience on 72 cases
Negative / Null Result ReportPolarity and timing-dependent effects of transcranial direct current stimulation in explicit motor learning
Negative / Null Result ReportThe feedback-related negativity (FRN) revisited: New insights into the localization, meaning and network organization
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: OpenAlex · DOI 10.1038/tp.2015.36