e-ISSN: Pending
Replication FailureOpen accessMedicine

IL-10-STAT3 axis preserves epithelial mitochondrial homeostasis during bacterial challenge.

Navaneetha Krishnan S; Jaiswal A; Mohan A; Wang A; E Shutt T; McKay DM · 2026 · Gut microbes

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Increasing evidence implicates mitochondrial dysfunction in the pathogenesis of inflammatory bowel disease (IBD), with the IBD-associated pathobiont adherent-invasive E. coli -LF82 (AIEC) promoting epithelial mitochondrial depolarization…

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Metadata source: Europe PMC · DOI 10.1080/19490976.2026.2661411