Design, power, and alpha levels in randomized phase II oncology trials.
Haslam A; Olivier T; Prasad V · 2023 · ESMO open
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Abstract (excerpt)
Background The statistical plan of a phase II trial should balance minimizing the premature termination of potentially beneficial therapies (i.e. false negatives) and the further, costly testing of ineffective drugs (i.e. false positives).…
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Metadata source: Europe PMC · DOI 10.1016/j.esmoop.2022.100779