Phenotypic spectrum and molecular characteristics of variants of uncertain significance in copy number variations associated with fetal cardiac malformations: a case series of 9 patients.
Yin J; Wang Q; Lan T; Ou H; Zhou X; Zhong L; Cao H; Zhang L · 2026 · Frontiers in pediatrics
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background Copy number variants of uncertain significance (VUS-CNVs) pose significant challenges in prenatal counseling for congenital heart malformations (CHMs). Their clinical relevance remains poorly defined, particularly in the absence…
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Metadata source: Europe PMC · DOI 10.3389/fped.2026.1696089