Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study
Heikki Joensuu; Filippo de Braud; G Grignagni; Tommaso De Pas; Giosafat Spitalieri; Paola Coco; Carlo Spreafico; S. Boselli · 2011 · British Journal of Cancer
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
BACKGROUND: Vatalanib (PTK787/ZK 222584) inhibits a few tyrosine kinases including KIT, platelet-derived growth factor receptors (PDGFRs) and vascular endothelial growth factor receptors (VEGFRs). We report efficacy and safety results of…
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Metadata source: OpenAlex · DOI 10.1038/bjc.2011.151