Effect of corticosteroids on the clinical course of community-acquired pneumonia: a randomized controlled trial
Silvia Fernández-Serrano; Jordi Dorca; Carolina García‐Vidal; Núria Sabé; Jordi Carratalà; Ana Fernández-Agüera; Mercè Corominas; Susana Padrones · 2011 · Critical Care
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
INTRODUCTION: The benefit of corticosteroids as adjunctive treatment in patients with severe community-acquired pneumonia (CAP) requiring hospital admission remains unclear. This study aimed to evaluate the impact of corticosteroid treatment on outcomes in patients with CAP. METHODS: This was a prospective, double-blind and randomized study. All patients received treatment with ceftriaxone plus levofloxacin and methyl-prednisolone (MPDN) administered randomly and blindly as an initial bolus, followed by a tapering regimen, or placebo. RESULTS: Of the 56 patients included in the study, 28 (50%)
Abstract by Silvia Fernández-Serrano; Jordi Dorca; Carolina García‐Vidal; Núria Sabé; Jordi Carratalà; Ana Fernández-Agüera; Mercè Corominas; Susana Padrones, Critical Care (2011) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1186/cc10103