Negative / Null Result ReportOpen accessMedicine· cited by 33

Prognostic factors of BRAF V600E colorectal cancer with liver metastases: a retrospective multicentric study

Sahir Javed; Stéphane Benoist; Patrick Devos; Stéphanie Truant; Rosine Guimbaud; Astrid Lièvre; David Sefrioui; Romain Cohen · 2022 · World Journal of Surgical Oncology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

BACKGROUND: BRAF V600E-mutant colorectal cancers (CRCs) are associated with shorter survival than BRAF wild-type tumors. Therapeutic decision-making for colorectal liver metastases (CRLM) harboring this mutation remains difficult due to the scarce literature. The aim was to study a large cohort of BRAF V600E-mutant CRLM patients in order to see if surgery extend overall survival among others prognostic factors. METHODS: BRAF V600E-mutant CRCs diagnosed with liver-only metastases, resected or not, were retrospectively identified between April 2008 and December 2017, in 25 French centers. Clinic

Abstract by Sahir Javed; Stéphane Benoist; Patrick Devos; Stéphanie Truant; Rosine Guimbaud; Astrid Lièvre; David Sefrioui; Romain Cohen, World Journal of Surgical Oncology (2022) — licensed CC BY 4.0.

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