Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study
Karl Ove Hufthammer; Trond Markestad; Claus Klingenberg; Arild E Rønnestad; Hallvard Reigstad; Hans Jørgen Stensvold · 2022 · BMJ Paediatrics Open
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Objective To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks.Setting All neonatal intensive care units (NICUs) in Norway during 2012–2018.Methods Defined population-based data were prospectively entered into a national registry. We compared LISA infants with all non-LISA infants and with non-LISA infants who received surfactant following intubation. We used propensity score (PS) matching to identify non-LISA infants who were similar regarding potential confounders.Main outco
Abstract by Karl Ove Hufthammer; Trond Markestad; Claus Klingenberg; Arild E Rønnestad; Hallvard Reigstad; Hans Jørgen Stensvold, BMJ Paediatrics Open (2022) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1136/bmjpo-2022-001527