The role of plasma inflammatory markers in late-life depression and conversion to dementia: a 3-year follow-up study
Mariia Bocharova; Tom Borza; Leiv Otto Watne; Knut Engedal; John T. O’Brien; Geir Selbæk; Ane Victoria Idland; John Hodsoll · 2025 · Molecular Psychiatry
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Late-life depression (LLD) has been linked to increased likelihood of dementia, although mechanisms responsible for this association remain largely unknown. One feature frequently observed in both LLD and dementia is elevated levels of plasma inflammatory markers. The present study aimed to compare the levels of 12 plasma inflammatory markers between older people with LLD and controls, and to explore whether these markers, along with clinical characteristics, can predict dementia in patients with LLD within 3 years of follow-up. Using multiple linear regression with stepwise adjustment, we com
Abstract by Mariia Bocharova; Tom Borza; Leiv Otto Watne; Knut Engedal; John T. O’Brien; Geir Selbæk; Ane Victoria Idland; John Hodsoll, Molecular Psychiatry (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41380-025-02908-2