Investigation of malondialdehyde as a trait marker associated with familial risk in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives - A longitudinal cohort study.
Coello K; Stanislaus S; Forman JL; Kjærstad HL; Ormstrup Sletved KS; Miskowiak KW; Faurholt-Jepsen M; Munkholm K · 2025 · Free radical biology & medicine
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Abstract (excerpt)
Aims Increased oxidative stress-generated tissue damage seems to play a pivotal role in the pathophysiology and progression of bipolar disorder (BD). Malondialdehyde (MDA), a product of lipid oxidation, may represent a trait marker in BD…
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Metadata source: Europe PMC · DOI 10.1016/j.freeradbiomed.2025.03.041