Preoperative 15 mg of melatonin for reducing anxiety and post-traumatic stress disorder symptoms in mandibular third molar surgery: A randomized double-blind placebo-controlled clinical trial.
Rosa HH; Ruppel C; Trappel ND; Goncalves RC; Bortoluzzi MC · 2026 · Medicina oral, patologia oral y cirugia bucal
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background This study evaluated the efficacy of a single 15 mg preoperative sublingual dose of melatonin in reducing anxiety as the primary outcome, and its effects on psychomotor performance, postoperative sleep quality, and early…
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Metadata source: Europe PMC · DOI 10.4317/medoral.27846