P0603 Early tumour necrosis factor inhibitor initiation is associated with increased persistence in Crohn’s Disease but not Ulcerative Colitis, whereas early ustekinumab, vedolizumab and tofacitinib did not improve persistence
B Gu; J Chetwood; A Pudipeddi; Y Yau; V Kariyawasam; S Paramsothy; R W Leong · 2026 · Journal of Crohn’s and Colitis
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Abstract Background Emerging evidence suggests early initiation of advanced therapies (AT) may improve outcomes, but optimal timing remains unclear. We aimed to assess the impact of AT timing on persistence. Methods We interrogated the…
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Metadata source: Crossref · DOI 10.1093/ecco-jcc/jjaf231.784