e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine

Reldesemtiv in Amyotrophic Lateral Sclerosis: Results From the COURAGE-ALS Randomized Clinical Trial.

Shefner JM; Cudkowicz ME; Genge A; Hardiman O; Al-Chalabi A; Andrews JA; Chio A; Corcia P · 2025 · JAMA neurology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Importance Treatment options for amyotrophic lateral sclerosis (ALS) remain suboptimal. Results from a phase 2 study of reldesemtiv in ALS suggested that it may slow disease progression. Objective To assess the effect of reldesemtiv vs…

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Metadata source: Europe PMC · DOI 10.1001/jamaneurol.2025.0241