e-ISSN: Pending
Negative / Null Result ReportOpen accessMedicine

The effect of sodium bicarbonate mini-tablets in a carbohydrate hydrogel on prolonged high-intensity cycling performance and metabolism in acute normobaric hypoxia.

Shannon ES; Sparks SA; McNaughton LR; Marrin K; Bridge CA · 2026 · European journal of applied physiology

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

PURPOSE: Hydrogen cation (H+) accumulation is exacerbated in hypoxia. Sodium bicarbonate (NaHCO3) ingestion can reduce fatigue associated with high-intensity exercise performance by counteracting H+ ion accumulation. The present study…

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Metadata source: Europe PMC · DOI 10.1007/s00421-025-06069-6