A test of the stochastic theory of stem cell differentiation
Bjerknes, M. · 1986
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“While I found ample evidence of production of new crypts from direct in vivo studies in adult mice, I failed to find evidence of crypt loss.”
Abstract (excerpt)
Stochastic theories of stem cell renewal are shown to predict turnover of intestinal crypts. While I found ample evidence of production of new crypts from direct in vivo studies in adult mice, I failed to find evidence of crypt loss. Thus,…
Excerpt shown for reference under fair use — read the full paper at the publisher.
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Metadata source: CORE · DOI 10.1016/s0006-3495(86)83751-1