Design and baseline characteristics of the LANDMARK study
Etsuro Ogata; Masafumi Fukagawa; Hideki Hirakata; Hideaki Kaneda; Tatsuo Kagimura; Tadao Akizawa; On behalf of the LANDMARK Study Group · 2016 · Clinical and Experimental Nephrology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Calcium (Ca)-based phosphate (P) binders, compared to non-Ca-based P binders, contribute to vascular calcification, which is associated with cardiovascular events. METHODS: The LANDMARK study is a multicenter, randomized, open-label, parallel comparative study of lanthanum carbonate (LC) and calcium carbonate (CC) in hemodialysis patients. Stable hemodialysis patients with intact parathyroid hormone ≤240 pg/mL meeting ≥1 of the following criteria (age >65 years, postmenopause, diabetes mellitus) were randomized into the LC and CC groups. LC group patients initially received LC 750
Abstract by Etsuro Ogata; Masafumi Fukagawa; Hideki Hirakata; Hideaki Kaneda; Tatsuo Kagimura; Tadao Akizawa; On behalf of the LANDMARK Study Group, Clinical and Experimental Nephrology (2016) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1007/s10157-016-1310-8