SMYD2 inhibitors have no effect in improving non-alcoholic steatohepatitis in mice.
Yang L; Zhuo S; Zhu X; Zhang X; Wang Z; Chen Y · 2025 · Frontiers in endocrinology
WASTE classifies this as Failed Experiment Report · AI classification, approximate
An experimental approach did not work as intended — learn what to avoid before investing the same effort.
Abstract (excerpt)
Introduction Nonalcoholic steatohepatitis (NASH), characterized by progressive liver injury, inflammation, and fibrosis, is a leading chronic liver disease worldwide. Pharmacotherapy for NASH is thus urgently needed. Through a strategy of…
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Metadata source: Europe PMC · DOI 10.3389/fendo.2025.1480453