Tirzepatide on obstructive sleep apnea-related cardiometabolic risk: secondary outcomes of the SURMOUNT-OSA randomized trial
Atul Malhotra; R GRUNSTEIN; Ali Azarbarzin; SA Sands; Virend K. Somers; Louis J. Aronne; Ania M. Jastreboff; Jitong Lou · 2026 · Nature Medicine
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Obstructive sleep apnea (OSA) is associated with obesity and cardiovascular risk. The SURMOUNT-OSA master protocol comprised two, 52-week, randomized, double-blind, placebo-controlled phase 3 studies (study 1 and study 2) and demonstrated…
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Metadata source: OpenAlex · DOI 10.1038/s41591-025-04071-1