No significant association of serum klotho concentration with blood pressure and pulse wave velocity in a Chinese population
Wanying Liang; Lihong Wang; Jian‐Hang Wei; Qinglu Li; Qiyan Li; Quan Liang; Nai‐Qing Hu; Lihua Li · 2021 · Scientific Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Klotho, an important anti-aging protein, may be related to elevated blood pressure (BP) and arterial stiffness. We aimed to investigate associations between the serum klotho concentration and peripheral/central BP and arterial stiffness based on the carotid-femoral pulse wave velocity (cfPWV) in a Chinese population. We invited all inhabitants aged ≥ 18 years in two Dali communities for participation. The SphygmoCor system was used to record radial arterial waveforms. Aortic waveforms were derived using a generalized transfer function. The central BP was assessed by calibrating the brachial BP
Abstract by Wanying Liang; Lihong Wang; Jian‐Hang Wei; Qinglu Li; Qiyan Li; Quan Liang; Nai‐Qing Hu; Lihua Li, Scientific Reports (2021) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41598-021-82258-5