Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model
Timothy P. LaBranche; Alison M. Bendele; Brian C Omura; Kathryn E. Gropp; Susan Hurst; Cedo M. Bagi; Thomas Cummings; Lonnie E. Grantham · 2016 · Annals of the Rheumatic Diseases
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
OBJECTIVE: To investigate whether the effects of nerve growth factor (NGF) inhibition with tanezumab on rats with medial meniscal tear (MMT) effectively model rapidly progressive osteoarthritis (RPOA) observed in clinical trials. METHODS:…
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Metadata source: OpenAlex · DOI 10.1136/annrheumdis-2015-208913