Srs2 functions needed to replicate CAG/CTG hairpins and prevent repeat instability
Jennifer Nguyen; Ranjith Anand; Guy-Franck Richard; Catherine Freudenreich · 2012 · The FASEB Journal
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Trinucleotide repeats form secondary DNA structures that can lead to chromosomal instability, breakage, and fork stalling during replication. Srs2, a non‐replicative helicase, anti‐recombinase that can displace Rad51, and interacts with…
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Metadata source: Crossref · DOI 10.1096/fasebj.26.1_supplement.741.2