Ocular Surface Ion Transport and Dry Eye Disease
Ethan S. Lindgren; Onur Çil; A. S. Verkman; Neel D. Pasricha · 2022 · Current Ophthalmology Reports
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Purpose of Review: To review the role of ocular surface epithelial (corneal and conjunctival) ion transporters in the pathogenesis and treatment of dry eye disease (DED). Recent Findings: Currently, anti-inflammatory agents are the mainstay of DED treatment, though there are several agents in development that target ion transport proteins on the ocular surface, acting by pro-secretory or anti-absorptive mechanisms to increase the tear fluid Film volume. Activation or inhibition of selected ion transporters can alter tear fluid osmolality, driving water transport onto the ocular surface via osm
Abstract by Ethan S. Lindgren; Onur Çil; A. S. Verkman; Neel D. Pasricha, Current Ophthalmology Reports (2022) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1007/s40135-022-00295-3