BDNF rs6265 polymorphism is not associated with the occurrence of overactive bladder and its response to intradetrusor injection of botulinum neurotoxin type A in female patients.
Ciećwież SM; Lewandowska K; Boroń A; Kotlęga D; Kociszewski J; Grocholewicz K; Clark JS; Ciechanowicz A · 2026 · Scientific reports
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Reports suggest increased urinary excretion of Brain-Derived Neurotrophic Factor in patients with Overactive Bladder (OAB). The rs6265 (c.196G > A, p.Val66Met) polymorphism in the BDNF gene was previously associated with impaired secretion…
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Metadata source: Europe PMC · DOI 10.1038/s41598-026-58792-5