e-ISSN: Pending
Replication FailureOpen accessMedicine· cited by 10

Randomized Sham-controlled Trial of Targeted Lung Denervation in Patients with Chronic Obstructive Pulmonary Disease (AIRFLOW-3)

Pallav L. Shah; Dirk‐Jan Slebos; Richard Sue; Surya P. Bhatt; Christian Ghattas; Charlie Strange; Bruno Degano; Arschang Valipour · 2025 · American Journal of Respiratory and Critical Care Medicine

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Abstract Rationale AIRFLOW-3 was a 1:1 randomized, double-blind, sham-controlled trial of the D’Nerva targeted lung denervation (TLD) system in patients with chronic obstructive pulmonary disease (COPD). Objective To evaluate the impact of…

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Metadata source: OpenAlex · DOI 10.1164/rccm.202502-0404oc