Influence of B cell-lineage targeted CAR-T cell therapy on humoral immunity and vaccine-induced antibody response
Stosh Ozog; Elizabeth M. Krantz; Karyn Tindbaek; Julian Munoz; Winnie L. Liu; Clementine Chalal; Sara Pernikoff; Khaleel Yahya · 2026 · Nature Communications
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Abstract Humoral immune-related adverse events, including hypogammaglobulinemia and B cell depletion, pose long-term infection risks after chimeric antigen receptor T cell therapy (CARTx) for hematologic malignancies. This prospective…
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Metadata source: OpenAlex · DOI 10.1038/s41467-026-71473-1