Exposure to Phthalates Affects Calcium Handling and Intercellular Connectivity of Human Stem Cell-Derived Cardiomyocytes
Nikki Gillum Posnack; Rabia Idrees; Hao Ding; Rafael Jaimes; Gulnaz Stybayeva; Zaruhi Karabekian; Michael A. Laflamme; Narine Sarvazyan · 2015 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: The pervasive nature of plastics has raised concerns about the impact of continuous exposure to plastic additives on human health. Of particular concern is the use of phthalates in the production of flexible polyvinyl chloride (PVC) products. Di-2-ethylhexyl-phthalate (DEHP) is a commonly used phthalate ester plasticizer that imparts flexibility and elasticity to PVC products. Recent epidemiological studies have reported correlations between urinary phthalate concentrations and cardiovascular disease, including an increased risk of high blood pressure and coronary risk. Yet, there
Abstract by Nikki Gillum Posnack; Rabia Idrees; Hao Ding; Rafael Jaimes; Gulnaz Stybayeva; Zaruhi Karabekian; Michael A. Laflamme; Narine Sarvazyan, PLoS ONE (2015) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0121927