Pre-Analytical and Analytical Challenges in Whole-Exome Sequencing of Formalin-Fixed Paraffin-Embedded Breast and Prostate Cancer Tissue: A Real-World Multicenter Study.
Rosa ML; Bordignon C; Schuch JB; Baumont AC; Bessel M; Curzel GD; Cadore NA; Varela APM · 2026 · Diagnostics (Basel, Switzerland)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Background/Objectives : Formalin-fixed paraffin-embedded tissue is widely used in pathology and molecular diagnostics, yet its variable quality can critically influence the accuracy of sequencing-based analyses. This study investigated…
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Metadata source: Europe PMC · DOI 10.3390/diagnostics16111595