When Randomization Is Not Enough: Divergent Beta-Blocker Trials and the Illusion of Universal Causality.
Omerovic E; Råmunddal T; Jha S; Petursson P; Skoglundv K; Rawshani A; Redfors B · 2026 · European heart journal. Cardiovascular pharmacotherapy
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Two contemporary randomized trials of β-blocker therapy after myocardial infarction (MI) reached apparently conflicting conclusions. REBOOT, conducted in Spain and Italy, found no reduction in death or major cardiovascular events among…
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Metadata source: Europe PMC · DOI 10.1093/ehjcvp/pvag037