Impact of fludarabine dosage on outcomes in large B-cell lymphoma patients treated with CAR T-cell therapy: a retrospective study of the CTIWP of the EBMT.
Dachy G; Mooyaart JE; Gabellier L; Yakoub-Agha I; Daskalakis M; Potter V; Dreger P; Huynh A · 2026 · Bone marrow transplantation
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Lymphodepleting conditioning (LD) with fludarabine and cyclophosphamide is critical to ensure optimal expansion and persistence of CD19 CAR T-cells. We conducted a retrospective EBMT registry study to assess the impact of fludarabine…
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Metadata source: Europe PMC · DOI 10.1038/s41409-026-02925-x