Schisandrin B exacerbates acute pancreatitis by driving pathological pancreatic secretion
Ye J; Hoàng DĐ; Liu X; Lin L; Ding Y · 2025 · Biochemical and Biophysical Research Communications
WASTE classifies this as Replication Failure · AI classification, approximate
A previously reported effect did not replicate here — verify it holds before you build on it.
Abstract (excerpt)
Schisandrin B (SchB), a natural lignan with reported organ-protective effects, was hypothesized to ameliorate severe acute pancreatitis (SAP). We investigated the effects of SchB (30 and 60 mg/kg) in a caerulein-induced mouse model of SAP…
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Metadata source: Europe PMC