Intravenous IRON supplementation in Heart Failure with Preserved Ejection Fraction and iron deficiency (IRON-HFpEF): a comprehensive phase II multicentre placebo-controlled randomised clinical trial.
van de Bovenkamp AA; Nassiri S; de Man FS; Oosterveer FPT; Mourmans SGJ; van Raalte DH; Dijkmans PA; van Heerebeek L · 2026 · European journal of heart failure
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Aims Iron deficiency (ID) is common in patients with heart failure with preserved ejection fraction (HFpEF). The IRON-HFpEF trial aimed to evaluate the mechanistic effects of intravenous iron supplementation on cardiovascular function and…
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Metadata source: Europe PMC · DOI 10.1093/ejhf/xuag162